THP-PEG7
Modify Date: 2025-10-04 19:16:21
THP-PEG7 structure
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Common Name | THP-PEG7 | ||
|---|---|---|---|---|
| CAS Number | 42607-87-4 | Molecular Weight | 232.23900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H34O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of THP-PEG7THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. |
| Name | 5,5-Dimethyl-4-methoxy-3-oxazolin-2-on |
|---|---|
| Synonym | More Synonyms |
| Description | THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Non-cleavable |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2]. |
| References |
| Molecular Formula | C17H34O8 |
|---|---|
| Molecular Weight | 232.23900 |
| Exact Mass | 232.09600 |
| PSA | 69.90000 |
| LogP | 0.90320 |
| InChIKey | ABJWCLPYMPRGRB-UHFFFAOYSA-N |
| SMILES | OCCOCCOCCOCCOCCOCCOC1CCCCO1 |
| Hazard Codes | Xi |
|---|
| Precursor 0 | |
|---|---|
| DownStream 2 | |
CAS#:3386-18-3
CAS#:868594-48-3| 4-methoxy-5,5-dimethyl-5H-oxazol-2-one |
| 4-Methoxy-5,5-dimethyl-5H-oxazol-2-on |