THP-PEG8-Tos

Modify Date: 2024-01-13 20:49:34

THP-PEG8-Tos structure	Common Name	THP-PEG8-Tos
	CAS Number	669556-37-0	Molecular Weight	520.63300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₄₀O₁₀S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of THP-PEG8-Tos

THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	17-(tetrahydro-2H-pyran-2-yloxy)-3,6,9,12,15-pentaoxaheptadecyl 4-methylbenzenesulfonate
Synonym	More Synonyms

Description	THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₄H₄₀O₁₀S
Molecular Weight	520.63300
Exact Mass	520.23400
PSA	116.36000
LogP	3.40730

Precursor 0
DownStream 3
CAS#:39160-70-8 Amino-PEG6-alcohol CAS#:3386-18-3 nonaethylene glycol CAS#:868594-48-3 Benzyl-PEG9-alcohol

17-[(tetrahydro-2H-pyran-2-yl)oxy]-1-tosyloxy-3,6,9,12,15-pentaoxaheptadecane

1-(2H-tetrahydropyran-2-yloxy)-17-tosyloxy-3,6,9,12,15-pentaoxaheptadecane

DC Chemicals Limited
China
Product Name: THP-PEG8-Tos
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: THP-PEG8-Tos
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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