146395-14-4
146395-14-4 structure
- Name: THP-PEG5-OH
- Chemical Name: THP-PEG6
- CAS Number: 146395-14-4
- Molecular Formula: C15H30O7
- Molecular Weight: 322.395
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-12-03 19:55:46
- Modify Date: 2024-01-05 13:00:06
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THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | THP-PEG6 |
|---|---|
| Synonyms |
3,6,9,12-Tetraoxatetradecan-1-ol, 14-[(tetrahydro-2H-pyran-2-yl)oxy]-
14-(Tetrahydro-2H-pyran-2-yloxy)-3,6,9,12-tetraoxatetradecan-1-ol MFCD26793753 |
| Description | THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 432.5±45.0 °C at 760 mmHg |
| Molecular Formula | C15H30O7 |
| Molecular Weight | 322.395 |
| Flash Point | 215.4±28.7 °C |
| Exact Mass | 322.199158 |
| LogP | -1.82 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.469 |