Methyl vanillate

Modify Date: 2024-01-03 17:32:22

Methyl vanillate structure	Common Name	Methyl vanillate
	CAS Number	3943-74-6	Molecular Weight	182.173
	Density	1.2±0.1 g/cm3	Boiling Point	286.0±0.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₀O₄	Melting Point	64-67 °C(lit.)
	MSDS	Chinese USA	Flash Point	120.2±15.8 °C
	Symbol	GHS07	Signal Word	Warning

Use of Methyl vanillate

Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

Name	methyl vanillate
Synonym	More Synonyms

Description	Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> Wnt Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology
Target	Wnt/β-catenin[1]
In Vitro	Methyl vanillate (0-100 μM) increases the expression and nuclear translocation of β-catenin in calvarial osteoblasts. Methyl vanillate dose-dependently elevates ALP activity in calvarial osteoblasts[1].
References	[1]. Cha PH, et al. Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. PLoS One. 2014 Jan 22;9(1):e85546.

Density	1.2±0.1 g/cm3
Boiling Point	286.0±0.0 °C at 760 mmHg
Melting Point	64-67 °C(lit.)
Molecular Formula	C₉H₁₀O₄
Molecular Weight	182.173
Flash Point	120.2±15.8 °C
Exact Mass	182.057907
PSA	55.76000
LogP	1.54
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.534
Storage condition	Room temperature.

Methyl vanillate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DH2430000

CHEMICAL NAME :: Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester

CAS REGISTRY NUMBER :: 3943-74-6

BEILSTEIN REFERENCE NO. :: 1369113

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H10-O4

MOLECULAR WEIGHT :: 182.19

WISWESSER LINE NOTATION :: 1OVR DQ CO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#06782

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DH2430000
HS Code	2918990090

Precursor 9
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DownStream 10
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HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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A series of 33 novel divanillates and trivanillates were synthesized and found to possess promising cytostatic rather than cytotoxic properties. Several compounds under study decreased by >50% the act...

The influence of heat on the aroma of cloudberries (rubus Chamaemorus l.).

Z. Lebensm. Unters. Forsch. 163(1) , 25-30, (1977)

The qualitative and quantitative differences between the volatiles of fresh and heated cloudberries have been evaluated and the significance of the differences calculated. 14 new cloudberry volatiles ...

Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.

J. Nat. Prod. 69 , 662-4, (2006)

Three linear sesquiterpene lactones, anthecotulide (1), hydroxyanthecotulide (2), and acetoxyanthecotulide (3), were isolated from the aerial parts of Anthemis auriculata. Five known flavonoids, tarax...

4-Hydroxy-3-methoxybenzoic Acid Methyl Ester

Methyl 4-hydroxy-3-methoxybenzoate

MFCD00008438

Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester

Vanillic Acid Methyl Ester

Vanillic acid, methyl ester (8CI)

Methyl vanillate

EINECS 223-525-9

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Methyl vanillate
Price: ￥188.0/25g ￥568.0/100g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Methyl vanillate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Methyl vanillate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Methyl vanillate
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Methyl vanillate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: ￥550/10 mM * 1 mL in DMSO

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Methyl vanillate

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