Journal of Natural Products 2006-04-01

Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity.

Revecca Theodori, Anastasia Karioti, Ana Rancić, Helen Skaltsa

Index: J. Nat. Prod. 69 , 662-4, (2006)

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Abstract

Three linear sesquiterpene lactones, anthecotulide (1), hydroxyanthecotulide (2), and acetoxyanthecotulide (3), were isolated from the aerial parts of Anthemis auriculata. Five known flavonoids, taraxa-20(30)en-3beta-ol (4), and methyl vanillate (5) were also isolated. The structures and the relative configuration of the new compounds 2 and 3 were deduced by spectroscopic methods. The in vitro activity of compounds 1-5 against 10 bacterial species and one fungus was tested using the microdilution method.