Rubrofusarin

Modify Date: 2025-09-18 11:13:52

Rubrofusarin Structure
Rubrofusarin structure
Common Name Rubrofusarin
CAS Number 3567-00-8 Molecular Weight 272.25300
Density 1.432g/cm3 Boiling Point 438.7ºC at 760mmHg
Molecular Formula C15H12O5 Melting Point 210 - 211 °C
MSDS N/A Flash Point 167ºC

 Use of Rubrofusarin


Rubrofusarin is an orange polyketide pigment from Fusarium graminearum[1]. Rubrofusarin is also an active ingredient of the Cassia species and ameliorates chronic restraint stress (CRS) -induced depressive symptoms through PI3K/Akt signaling. Rubrofusarin has anticancer, antibacterial, and antioxidant effects[2][3].

 Names

Name rubrofusarin
Synonym More Synonyms

 Rubrofusarin Biological Activity

Description Rubrofusarin is an orange polyketide pigment from Fusarium graminearum[1]. Rubrofusarin is also an active ingredient of the Cassia species and ameliorates chronic restraint stress (CRS) -induced depressive symptoms through PI3K/Akt signaling. Rubrofusarin has anticancer, antibacterial, and antioxidant effects[2][3].
Related Catalog
References

[1]. Hiroshi Tanaka, et al. The Chemical Constitution of Rubrofusarin, a Pigment from Fusarium graminearum. Agricultural and Biological Chemistry, 26:11, 767-770.

[2]. Peter Rugbjerg, et al. Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae. Microb Cell Fact. 2013 Apr 4;12:31.

[3]. Jee Hyun Yi , et al. Rubrofusarin Attenuates Chronic Restraint Stress-Induced Depressive Symptoms. Int J Mol Sci. 2020 May 13;21(10):3454.

 Chemical & Physical Properties

Density 1.432g/cm3
Boiling Point 438.7ºC at 760mmHg
Melting Point 210 - 211 °C
Molecular Formula C15H12O5
Molecular Weight 272.25300
Flash Point 167ºC
Exact Mass 272.06800
PSA 79.90000
LogP 2.67440
Index of Refraction 1.691
Storage condition 20°C

 Safety Information

Hazard Codes Xi
HS Code 2914509090

 Synthetic Route

~73%

Rubrofusarin Structure

Rubrofusarin

CAS#:3567-00-8

Literature: Abell, Chris; Bush, Brian D.; Staunton, James Journal of the Chemical Society, Chemical Communications, 1986 , # 1 p. 15 - 17

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Rubrofusarin Structure

Rubrofusarin

CAS#:3567-00-8

Literature: Kitanaka, Susumu; Takido, Michio Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 10 p. 3980 - 3984

 Precursor & DownStream

Precursor  1

DownStream  1

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

rubrofusarin B
5,6-Dihydroxy-8-methoxy-2-methyl-4H-naphtho<2,3-b>pyran-4-on
Rubrofusarin
RUBRAFUSARIN
Rubofusarin
5,6-dihydroxy-8-methoxy-2-methylbenzo[g]chromen-4-one
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