2,2,2-Trifluoroethyl formate

Modify Date: 2025-08-26 20:25:07

2,2,2-Trifluoroethyl formate Structure
2,2,2-Trifluoroethyl formate structure
Common Name 2,2,2-Trifluoroethyl formate
CAS Number 32042-38-9 Molecular Weight 128.050
Density 1.3±0.1 g/cm3 Boiling Point 33.7±40.0 °C at 760 mmHg
Molecular Formula C3H3F3O2 Melting Point N/A
MSDS Chinese USA Flash Point -17.7±19.6 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Names

Name 2,2,2-trifluoroethyl formate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 33.7±40.0 °C at 760 mmHg
Molecular Formula C3H3F3O2
Molecular Weight 128.050
Flash Point -17.7±19.6 °C
Exact Mass 128.008514
PSA 26.30000
LogP 1.07
Vapour Pressure 547.2±0.1 mmHg at 25°C
Index of Refraction 1.300
InChIKey CAFROQYMUICGNO-UHFFFAOYSA-N
SMILES O=COCC(F)(F)F
Storage condition Flammables area

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H302-H319
Precautionary Statements P210-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F,Xn
Risk Phrases R11
Safety Phrases 26
RIDADR UN 1993 3/PG 2
Packaging Group II
Hazard Class 3.0
HS Code 2915120000

 Synthetic Route

~70%

2,2,2-Trifluoroethyl formate Structure

2,2,2-Trifluoro...

CAS#:32042-38-9

Literature: Hill, David R; Hsiao, Chi-Nung; Kurukulasuriya, Ravi; Wittenberger, Steven J Organic letters, 2002 , vol. 4, # 1 p. 111 - 113

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2,2,2-Trifluoroethyl formate Structure

2,2,2-Trifluoro...

CAS#:32042-38-9

Literature: US2002/19539 A1, ; US 20020019539 A1

~84%

2,2,2-Trifluoroethyl formate Structure

2,2,2-Trifluoro...

CAS#:32042-38-9

Literature: Environmental Science and Technology, , vol. 38, # 21 p. 5567 - 5576

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2,2,2-Trifluoroethyl formate Structure

2,2,2-Trifluoro...

CAS#:32042-38-9

Literature: Environmental Science and Technology, , vol. 36, # 14 p. 3118 - 3123

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2,2,2-Trifluoroethyl formate Structure

2,2,2-Trifluoro...

CAS#:32042-38-9

Literature: Chemical Physics Letters, , vol. 524, p. 32 - 37

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2,2,2-Trifluoroethyl formate Structure

2,2,2-Trifluoro...

CAS#:32042-38-9

Literature: ChemPhysChem, , vol. 14, # 16 p. 3834 - 3842

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2,2,2-Trifluoroethyl formate Structure

2,2,2-Trifluoro...

CAS#:32042-38-9

Literature: ChemPhysChem, , vol. 14, # 16 p. 3834 - 3842

 Customs

HS Code 2915120000
Summary 2915120000 salts of formic acid。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles1

More Articles
2,2,2-trifluoroethyl formate: a versatile and selective reagent for the formylation of alcohols, amines, and N-hydroxylamines.

Org. Lett. 4 , 111, (2002)

[reaction: see text] Treatment of a variety of alcohols, amines, and N-hydroxylamines with 2,2,2-trifluoroethyl formate gave the corresponding formylated adducts in high yields.

 Synonyms

Zayia's reagent
HCOOCH2CF3
TFEF
Formic Acid 2,2,2-Trifluoroethyl Ester
Ameisensaeure-2,2,2-trifluorethylester
Ethanol, 2,2,2-trifluoro-, formate
2,2,2-Trifluoroethyl formate
trifluoroethyl formate
2,2,2-trifluoroethylformate
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