L(+)-Ornithine hydrochloride

Modify Date: 2024-01-02 14:51:59

L(+)-Ornithine hydrochloride Structure
L(+)-Ornithine hydrochloride structure
Common Name L(+)-Ornithine hydrochloride
CAS Number 3184-13-2 Molecular Weight 168.622
Density 1.57 Boiling Point 308.7ºC at 760 mmHg
Molecular Formula C5H13ClN2O2 Melting Point 245 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 140.5ºC

 Use of L(+)-Ornithine hydrochloride


L-Ornithine Hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

 Names

Name L(+)-Ornithine hydrochloride
Synonym More Synonyms

 L(+)-Ornithine hydrochloride Biological Activity

Description L-Ornithine Hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Demura S, et al. Effect of L-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise. Eur J Appl Physiol. 2011 Nov;111(11):2837-43.

 Chemical & Physical Properties

Density 1.57
Boiling Point 308.7ºC at 760 mmHg
Melting Point 245 °C (dec.)(lit.)
Molecular Formula C5H13ClN2O2
Molecular Weight 168.622
Flash Point 140.5ºC
Exact Mass 168.066559
PSA 89.34000
LogP 1.33980
Index of Refraction 24 ° (C=4, 6mol/L HCl)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RM2985000
CHEMICAL NAME :
Ornithine, monohydrochloride, L-
CAS REGISTRY NUMBER :
3184-13-2
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H12-N2-O2.Cl-H
MOLECULAR WEIGHT :
168.65
WISWESSER LINE NOTATION :
Z3YZVQ &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,49,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4776 No. of Facilities: 162 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 2955 (estimated) No. of Female Employees: 2312 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS RM2985000
HS Code 2922499990

 Synthetic Route

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L(+)-Ornithine hydrochloride Structure

L(+)-Ornithine ...

CAS#:3184-13-2

Literature: European Journal of Organic Chemistry, , # 21 p. 4391 - 4396

~%

L(+)-Ornithine hydrochloride Structure

L(+)-Ornithine ...

CAS#:3184-13-2

Literature: European Journal of Organic Chemistry, , # 21 p. 4391 - 4396

~%

L(+)-Ornithine hydrochloride Structure

L(+)-Ornithine ...

CAS#:3184-13-2

Literature: Siebum, Arjan H. G.; Tsang, Robert K. F.; Van Der Steen, Rob; Raap, Jan; Lugtenburg, Johan European Journal of Organic Chemistry, 2004 , # 21 p. 4391 - 4396

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L(+)-Ornithine hydrochloride Structure

L(+)-Ornithine ...

CAS#:3184-13-2

Literature: Journal of Chemical Thermodynamics, , vol. 25, # 2 p. 293 - 305

 Preparation

3184-13-2 preparation

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles48

More Articles
Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.

Am. J. Respir. Cell. Mol. Biol. 48(6) , 694-702, (2013)

Up-regulation of arginase contributes to airways hyperresponsiveness (AHR) in asthma by reducing L-arginine bioavailability for the nitric oxide (NO) synthase isozymes. The product of arginase activit...

Microbacterium kyungheense sp. nov. and Microbacterium jejuense sp. nov., isolated from salty soil.

Int. J. Syst. Evol. Microbiol. 64(Pt 7) , 2267-73, (2014)

Two novel strains, THG-C26(T) and THG-C31(T), were characterized using a polyphasic approach to determine their taxonomic positions. These two isolates were aerobic, Gram-stain-positive, non-motile, n...

Treatment of arginase deficiency revisited: guanidinoacetate as a therapeutic target and biomarker for therapeutic monitoring.

Dev. Med. Child Neurol. 56(10) , 1021-4, (2014)

Hyperargininaemia is a disorder of the last step of the urea cycle. It is an autosomal recessive disease caused by deficiency of liver arginase-1 and usually presents later in childhood with progressi...

 Synonyms

L-Ornithine, monohydrochloride
H-Orn-OH.HCl
L-Orn hydrochloride
(2S)-2,5-diaminopentanoic acid hydrochloride
L-Ornithine monohydrochloride
L-Ornithine HCl
(S)-2,5-Diaminovaleric acid monohydrochloride
D-ORNITHINE HCL
L(+)-Ornithinehydrochloride
H-Orn-OH·HCl
(S)-2,5-Diaminopentanoic acid monohydrochloride
D-ORN,HCL
MFCD00012917
H-D-ORN HCL
L-ORN HCL
ORNITHINE HCL
L(+)-Ornithine Hydrochloride
L-Ornithine hydrochloride (1:1)
H-L-ORN-OH HCL
Z3YZVQ &&L or S Form HCl
(S)-(+)-2,5-Diaminopentanoic acid hydrochloride
H-D-ORN-OH HCL
(S)-2,5-Diaminopentanoic acid hydrochloride
L-Ornithine, hydrochloride (1:1)
EINECS 240-729-3
L-ornithine hydrochloride
Guanine Hydrochloride
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