LU AA33810

Modify Date: 2025-08-22 17:22:01

LU AA33810 Structure
LU AA33810 structure
Common Name LU AA33810
CAS Number 304008-29-5 Molecular Weight 423.61600
Density N/A Boiling Point N/A
Molecular Formula C19H25N3O2S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LU AA33810


Lu AA33810 is a potent and selective antagonist of neuropeptide Y5 receptor with a Ki of 1.5 nM for the human receptor. Lu AA33810 exhibts antianxiolytic-like and antidepressant-like effects[1].

 Names

Name N-{[trans-4-(4,5-Dihydro[1]benzothiepino[5,4-d][1,3]thiazol-2-yla mino)cyclohexyl]methyl}methanesulfonamide

 LU AA33810 Biological Activity

Description Lu AA33810 is a potent and selective antagonist of neuropeptide Y5 receptor with a Ki of 1.5 nM for the human receptor. Lu AA33810 exhibts antianxiolytic-like and antidepressant-like effects[1].
Related Catalog
Target

hY5 receptor:1.5 nM (Ki)

References

[1]. Walker MW, et al. The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity. J Pharmacol Exp Ther. 2009 Mar;328(3):900-11.

 Chemical & Physical Properties

Molecular Formula C19H25N3O2S3
Molecular Weight 423.61600
Exact Mass 423.11100
PSA 136.24000
LogP 4.87180
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