Toloxatone
Toloxatone structure
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Common Name | Toloxatone | ||
|---|---|---|---|---|
| CAS Number | 29218-27-7 | Molecular Weight | 207.23 | |
| Density | 1.245g/cm3 | Boiling Point | 358.9ºC at 760mmHg | |
| Molecular Formula | C11H13NO3 | Melting Point | 76° | |
| MSDS | Chinese USA | Flash Point | 170.9ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of ToloxatoneToloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor[1]. Antidepressant[1]. |
| Name | 2-oxazolidinone, 5-(hydroxymethyl)-3-(3-methylphenyl) |
|---|---|
| Synonym | More Synonyms |
| Description | Toloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor[1]. Antidepressant[1]. |
|---|---|
| Related Catalog | |
| Target |
MAOA[1] |
| References |
| Density | 1.245g/cm3 |
|---|---|
| Boiling Point | 358.9ºC at 760mmHg |
| Melting Point | 76° |
| Molecular Formula | C11H13NO3 |
| Molecular Weight | 207.23 |
| Flash Point | 170.9ºC |
| Exact Mass | 207.09000 |
| PSA | 49.77000 |
| LogP | 1.37750 |
| Vapour Pressure | 8.9E-06mmHg at 25°C |
| Index of Refraction | 1.57 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: >10mg/mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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5-(2-Aminopropyl)indole (5-IT): a psychoactive substance used for recreational purposes is an inhibitor of human monoamine oxidase (MAO).
Drug Test. Anal. 6(7-8) , 607-13, (2014) 5-(2-Aminopropyl)indole (5-IT) is a psychoactive compound that has recently been associated with several fatal and non-fatal intoxications in a number of European countries. There are indications that... |
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Comparison of Monoamine Oxidase Inhibitors in Decreasing Production of the Autotoxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde in PC12 Cells.
J. Pharmacol. Exp. Ther. 356 , 483-92, (2016) According to the catecholaldehyde hypothesis, the toxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL) contributes to the loss of nigrostriatal dopaminergic neurons in Parkinson's disease... |
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A double-blind comparison of moclobemide and toloxatone in out-patients presenting a major depressive disorder.
Psychopharmacology 106 Suppl , S118-9, (1992) A double-blind comparison of moclobemide and toloxatone was performed in adult out-patients diagnosed as suffering from a major depressive disorder. Parallel groups of patients received moclobemide, 4... |
| 5-(hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone Humoryl |
| Toloxatone |
| 5-(Hydroxymethyl)-3-(m-tolyl)oxazolidin-2-one |
| 5-hydroxymethyl-3-(3-methylphenyl)-2-oxazolidinone |
| ToloxatonetoloxatonetoloxatoneToloxatone |
| Perenum |
| EINECS 249-522-2 |
| MFCD00865391 |
| Humoryl |
| 5-(hydroxymethyl)-3-m-tolyl-2-oxazolidinone |
| 5-Hydroxymethyl-3-(3-methylphenyl)oxazolidin-2-one |