AKT-IN-8
Modify Date: 2025-08-26 23:06:21
AKT-IN-8 structure
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Common Name | AKT-IN-8 | ||
|---|---|---|---|---|
| CAS Number | 2654026-13-6 | Molecular Weight | 456.93 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H25ClN6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AKT-IN-8AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively[1]. |
| Name | AKT-IN-8 |
|---|
| Description | AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
Akt1:4.46 nM (IC50) Akt2:2.44 nM (IC50) Akt3:9.47 nM (IC50) |
| References |
[1]. Fused tetracyclic derivative, preparation method therefor, and medical use thereof. WO2021121276A1. |
| Molecular Formula | C22H25ClN6O3 |
|---|---|
| Molecular Weight | 456.93 |
| InChIKey | AWLFPOHXSPBHQB-PONJGIIJSA-N |
| SMILES | NC1(C(=O)NC(CCO)c2ccc(Cl)cc2)CCN2c3ncnc4[nH]cc(c34)OCC2C1 |