AKT-IN-8

Names

[ CAS No. ]:
2654026-13-6

[ Name ]:
AKT-IN-8

Biological Activity

[Description]:

AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PI3K/Akt/mTOR >> Akt

[Target]

Akt1:4.46 nM (IC50)

Akt2:2.44 nM (IC50)

Akt3:9.47 nM (IC50)


[References]

[1]. Fused tetracyclic derivative, preparation method therefor, and medical use thereof. WO2021121276A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H25ClN6O3

[ Molecular Weight ]:
456.93

Related Compounds