Captopril EP Impurity C

Modify Date: 2024-01-09 09:51:11

Captopril EP Impurity C Structure
Captopril EP Impurity C structure
Common Name Captopril EP Impurity C
CAS Number 26473-47-2 Molecular Weight 120.170
Density 1.2±0.1 g/cm3 Boiling Point 232.5±23.0 °C at 760 mmHg
Molecular Formula C4H8O2S Melting Point N/A
MSDS Chinese USA Flash Point 94.4±22.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Captopril EP Impurity C


Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].

 Names

Name 2-methyl-3-sulfanylpropanoic acid
Synonym More Synonyms

 Captopril EP Impurity C Biological Activity

Description Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].
Related Catalog
References

[1]. ANCA GABRIELA CÂRJE, et al. HPLC-UV METHOD APPROACH FOR THE ANALYSIS AND IMPURITY PROFILING OF CAPTOPRIL.

[2]. Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268.

[3]. Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 232.5±23.0 °C at 760 mmHg
Molecular Formula C4H8O2S
Molecular Weight 120.170
Flash Point 94.4±22.6 °C
Exact Mass 120.024498
PSA 76.10000
LogP 0.78
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.491

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
HS Code 2930909090

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles5

More Articles
The utilization of 3-mercapto-2-methylpropionate as sulphur source by a phototrophic bacterium.

Bioorg. Med. Chem. 2(7) , 589-93, (1994)

A bacterium (strain photoB) photoassimilated 3-mercapto-2-methylpropionate as sole source of sulphur with methacrylate accumulating in the medium. This was thought to be the product of a sulphur-lyase...

Bacterial taxa that limit sulfur flux from the ocean.

Science 314(5799) , 649-52, (2006)

Flux of dimethylsulfide (DMS) from ocean surface waters is the predominant natural source of sulfur to the atmosphere and influences climate by aerosol formation. Marine bacterioplankton regulate sulf...

Methylthiol:coenzyme M methyltransferase from Methanosarcina barkeri, an enzyme of methanogenesis from dimethylsulfide and methylmercaptopropionate.

J. Bacteriol. 179(22) , 6902-11, (1997)

During growth on acetate, Methanosarcina barkeri expresses catabolic enzymes for other methanogenic substrates such as monomethylamine. The range of substrates used by cells grown on acetate was furth...

 Synonyms

(2RS)-2-Methyl-3-sulphanylpropanoic acid 3-Mercaptoisobutyric acid
Captopril impurity C
EINECS 247-726-6
Propanoic acid, 3-mercapto-2-methyl-
3-sulfhydryl isobutyric acid
3-mercapto-2-methylpropionic acid
3-mercapto-2-methylpropanoic acid
3-Mercaptoisobutyric acid
MFCD00671555
UNII:V3E4016VAS
3-Mercapto-2-methyl propanoic acid
2-Methyl-3-sulfanylpropanoic acid
Captopril Impurity 3
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