β-Secretase Inhibitor II

Modify Date: 2024-01-16 12:10:33

β-Secretase Inhibitor II Structure
β-Secretase Inhibitor II structure
Common Name β-Secretase Inhibitor II
CAS Number 263563-09-3 Molecular Weight 461.59
Density N/A Boiling Point N/A
Molecular Formula C25H39N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of β-Secretase Inhibitor II


β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer's disease[1].

 Names

Name γ-Secretase Inhibitor II

 β-Secretase Inhibitor II Biological Activity

Description β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer's disease[1].
Related Catalog
Target

IC50: 700 nM (Aβ)[1]. IC50: 2.5 μM (Aβ1–42)[1]

In Vitro β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II inhibits the formation of both total Aβ and Aβ1–42 in a dose-dependent manner[1].
References

[1]. Abbenante, G., et al. Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site. Biochemical and Biophysical Research Communications. 2000; 268(1), 133–135.

 Chemical & Physical Properties

Molecular Formula C25H39N3O5
Molecular Weight 461.59