263563-09-3

263563-09-3 structure

Name: β-Secretase Inhibitor II
Chemical Name: γ-Secretase Inhibitor II
CAS Number: 263563-09-3
Molecular Formula: C₂₅H₃₉N₃O₅
Molecular Weight: 461.59
Catalog: Signaling Pathways Neuronal Signaling Beta-secretase
Create Date: 2018-06-13 17:18:37
Modify Date: 2025-08-26 11:46:25
β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer's disease[1].

Name	γ-Secretase Inhibitor II

Description	β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer's disease[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Neurological Disease
Target	IC50: 700 nM (Aβ)[1]. IC50: 2.5 μM (Aβ1–42)[1]
In Vitro	β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II inhibits the formation of both total Aβ and Aβ1–42 in a dose-dependent manner[1].
References	[1]. Abbenante, G., et al. Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site. Biochemical and Biophysical Research Communications. 2000; 268(1), 133–135.

Molecular Formula	C₂₅H₃₉N₃O₅
Molecular Weight	461.59