869577-51-5

869577-51-5 structure
869577-51-5 structure
  • Name: MMP-2 Inhibitor II
  • Chemical Name: MMP-2 Inhibitor II
  • CAS Number: 869577-51-5
  • Molecular Formula: C16H17NO6S2
  • Molecular Weight: 383.439
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
  • Create Date: 2021-05-16 22:29:55
  • Modify Date: 2025-08-25 18:50:07
  • MMP-2 Inhibitor II (compound 2) is a selective MMP-2 inhibitor. The Kinetic parameters for MMP inhibition are 2.4 μM (MMP-2), 45 μM (MMP-1), and 379 μM (MMP-7), respectively[1].

Name MMP-2 Inhibitor II
Synonyms Methanesulfonamide, N-[4-[4-[(oxiranylmethyl)sulfonyl]phenoxy]phenyl]-
N-(4-{4-[(2-Oxiranylmethyl)sulfonyl]phenoxy}phenyl)methanesulfonamide
MMP-2 Inhibitor II
Description MMP-2 Inhibitor II (compound 2) is a selective MMP-2 inhibitor. The Kinetic parameters for MMP inhibition are 2.4 μM (MMP-2), 45 μM (MMP-1), and 379 μM (MMP-7), respectively[1].
Related Catalog
Target

MMP-1:45 μM (Ki)

MMP-2:2.4 μM (Ki)

MMP-7:379 μM (Ki)

In Vitro 基质金属蛋白酶 (Matrix metalloproteinases, MMPs) 是锌依赖性内肽酶,在生理病理条件下起重要作用[1]。
References

[1]. Ikejiri M, et al. Potent mechanism-based inhibitors for matrix metalloproteinases. J Biol Chem. 2005 Oct 7;280(40):33992-4002.  

Density 1.5±0.1 g/cm3
Boiling Point 591.7±60.0 °C at 760 mmHg
Molecular Formula C16H17NO6S2
Molecular Weight 383.439
Flash Point 311.6±32.9 °C
Exact Mass 383.049713
LogP 2.24
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.624
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