mGAT3/4-IN-2

Modify Date: 2024-01-16 17:01:57

mGAT3/4-IN-2 structure	Common Name	mGAT3/4-IN-2
	CAS Number	2556833-68-0	Molecular Weight	502.13
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₂ClN₃OS₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of mGAT3/4-IN-2

mGAT3/4-IN-2 (compound 27b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.44 and 5.25, respectively[1].

Name	mGAT3/4-IN-2

Description	mGAT3/4-IN-2 (compound 27b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.44 and 5.25, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Target	pIC50: 5.12 ± 0.08 (mGAT1), 5.14 ± 0.07 (mGAT2), 5.44 ± 0.08 (mGAT3), 5.25 ± 0.04 (mGAT4)[1]
References	[1]. Zaręba P, et al. Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice. Eur J Med Chem. 2020 Feb 15;188:111920.

Molecular Formula	C₂₆H₃₂ClN₃OS₂
Molecular Weight	502.13