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2556833-68-0

2556833-68-0 structure

2556833-68-0 structure

Name: mGAT3/4-IN-2
Chemical Name: mGAT3/4-IN-2
CAS Number: 2556833-68-0
Molecular Formula: C₂₆H₃₂ClN₃OS₂
Molecular Weight: 502.13
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2022-07-11 09:29:05
Modify Date: 2025-08-28 20:02:24
mGAT3/4-IN-2 (compound 27b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.44 and 5.25, respectively[1].

Name	mGAT3/4-IN-2

Description	mGAT3/4-IN-2 (compound 27b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.44 and 5.25, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Target	pIC50: 5.12 ± 0.08 (mGAT1), 5.14 ± 0.07 (mGAT2), 5.44 ± 0.08 (mGAT3), 5.25 ± 0.04 (mGAT4)[1]
References	[1]. Zaręba P, et al. Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice. Eur J Med Chem. 2020 Feb 15;188:111920.

Molecular Formula	C₂₆H₃₂ClN₃OS₂
Molecular Weight	502.13

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