Mal-PEG4-C2-NH2 TFA

Modify Date: 2024-01-10 18:12:56

Mal-PEG4-C2-NH2 TFA Structure
Mal-PEG4-C2-NH2 TFA structure
Common Name Mal-PEG4-C2-NH2 TFA
CAS Number 2512227-13-1 Molecular Weight 430.37
Density N/A Boiling Point N/A
Molecular Formula C16H25F3N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG4-C2-NH2 TFA


Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG4-C2-NH2 TFA

 Mal-PEG4-C2-NH2 TFA Biological Activity

Description Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H25F3N2O8
Molecular Weight 430.37

 Safety Information

Hazard Codes Xi