Pom-8PEG

Modify Date: 2024-01-09 19:39:31

Pom-8PEG Structure
Pom-8PEG structure
Common Name Pom-8PEG
CAS Number 2488761-03-9 Molecular Weight 625.66
Density N/A Boiling Point N/A
Molecular Formula C29H43N3O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pom-8PEG


Pom-8PEG, an E3 ligase ligand-linker conjugate, incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and an 8-unit PEG linker. Pom-8PEG can be used in the synthesis of PROTAC, such as IDO1 PROTAC degrader[1].

 Names

Name Pom-8PEG

 Pom-8PEG Biological Activity

Description Pom-8PEG, an E3 ligase ligand-linker conjugate, incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and an 8-unit PEG linker. Pom-8PEG can be used in the synthesis of PROTAC, such as IDO1 PROTAC degrader[1].
Related Catalog
Target

Cereblon

References

[1]. Hu M, et al. Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1. Acta Pharm Sin B. 2020;10(10):1943-1953.

 Chemical & Physical Properties

Molecular Formula C29H43N3O12
Molecular Weight 625.66

 Safety Information

Hazard Codes Xi
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