Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Adefovir Dipivoxil
Price: ￥588.0/25mg ￥1998.0/100mg
Purity: 99.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Adefovir Dipivoxil
Price: $300.0/100mg $600.0/250mg $1000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Adefovir dipivoxil
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Atomoxetine Hydrochloride
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

142340-99-6

142340-99-6 structure

Name: Adefovir Dipivoxil
Chemical Name: Adefovir dipivoxil
CAS Number: 142340-99-6
Molecular Formula: C₂₀H₃₂N₅O₈P
Molecular Weight: 501.470
Catalog: API Synthetic anti-infective drugs Antiviral drugs
Create Date: 2018-02-07 08:00:00
Modify Date: 2024-01-02 06:37:33
Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.Target: NRTIs; HBVAdefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4].

Name	Adefovir dipivoxil
Synonyms	9-[2-[Bis(pivaloyloxymethoxy)phosphorylmethoxy]ethyl]adenine BIS POM PMEA ADEFOVIR PIVOXIL Adefovir Dipivoxil 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine Hepsera ADEFOVIR DIPVOXIL Preveon MFCD00869897 EINECS 200-001-8 ADEFOVIR DIPIVOLIX Adefovir Dipivoxyl Adefovir Dipivoxi Adefovir Dipivoxl Adefovir Impurity 3

Description	Adefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.Target: NRTIs; HBVAdefovir Dipivoxil works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir Dipivoxil is used for treatment of hepatitis B and herpes simplex virus infection [1-3]. Adefovir Dipivoxil is approved for the treatment of chronic hepatitis B in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (primarily ALT) or histologically active disease. Adefovir Dipivoxil is a failed treatment for HIV[3, 4].
Related Catalog	Signaling Pathways >> Anti-infection >> HBV Signaling Pathways >> Anti-infection >> Reverse Transcriptase Research Areas >> Infection
References	[1]. Marcellin, P., et al., Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med, 2003. 348(9): p. 808-16. [2]. Manolakopoulos, S., et al., Long-term therapy with adefovir dipivoxil in hepatitis B e antigen-negative patients developing resistance to lamivudine. Aliment Pharmacol Ther, 2008. 27(3): p. 266-73. [3]. Committee, A.I.S., A randomized placebo-controlled trial of adefovir dipivoxil in advanced HIV infection: the ADHOC trial. HIV Med, 2002. 3(4): p. 229-38. [4]. Fisher, E.J., et al., The safety and efficacy of adefovir dipivoxil in patients with advanced HIV disease: a randomized, placebo-controlled trial. AIDS, 2001. 15(13): p. 1695-700.

Density	1.4±0.1 g/cm3
Boiling Point	641.0±65.0 °C at 760 mmHg
Melting Point	98-102ºC
Molecular Formula	C₂₀H₃₂N₅O₈P
Molecular Weight	501.470
Flash Point	341.5±34.3 °C
Exact Mass	501.198853
PSA	176.79000
LogP	2.45
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.569
Storage condition	−20°C

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H332
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R20/21/22
Safety Phrases	36/37
RIDADR	NONH for all modes of transport