CDK1/Cyc B-IN-1

Modify Date: 2024-01-28 16:46:12

CDK1/Cyc B-IN-1 structure	Common Name	CDK1/Cyc B-IN-1
	CAS Number	2459916-56-2	Molecular Weight	353.85
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₂ClN₃O₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CDK1/Cyc B-IN-1

CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. CDK1/Cyc B-IN-1 triggers apoptosis and G2/M cell cycle arrest. CDK1/Cyc B-IN-1 shows broad-spectrum cytotoxic action against cancer cell lines[1].

Name	CDK1/Cyc B-IN-1

Description	CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. CDK1/Cyc B-IN-1 triggers apoptosis and G2/M cell cycle arrest. CDK1/Cyc B-IN-1 shows broad-spectrum cytotoxic action against cancer cell lines[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK1-Cyclin B:97 nM (IC50)
In Vitro	CDK1/Cyc B-IN-1 (Compound 5) shows cytotoxic activity with IC50 values of 5.33 ± 0.69 µM and 21.69 ± 1.04 µM against HCT-116 and WI-38, respectively[1].
References	[1]. Mohamed SH, et al. An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic properties. Bioorg Med Chem. 2020 Sep 1;28(17):115633.

Molecular Formula	C₁₄H₁₂ClN₃O₂S₂
Molecular Weight	353.85

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CDK1/Cyc B-IN-1

Use of CDK1/Cyc B-IN-1

Names

CDK1/Cyc B-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.