Aurora kinase inhibitor-9

Modify Date: 2025-10-04 15:53:11

Aurora kinase inhibitor-9 Structure
Aurora kinase inhibitor-9 structure
Common Name Aurora kinase inhibitor-9
CAS Number 2419107-09-6 Molecular Weight 454.33
Density N/A Boiling Point N/A
Molecular Formula C19H17Cl2N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aurora kinase inhibitor-9


Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity[1].

 Names

Name Aurora kinase inhibitor-9

 Aurora kinase inhibitor-9 Biological Activity

Description Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity[1].
Related Catalog
Target

Aurora A:0.093 μM (IC50)

Aurora B:0.09 μM (IC50)

References

[1]. Al-Sanea MM, et al. Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights. Bioorg Med Chem. 2020 Jul 1;28(13):115525.

 Chemical & Physical Properties

Molecular Formula C19H17Cl2N3O4S
Molecular Weight 454.33
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