2419107-09-6

2419107-09-6 structure

Name: Aurora kinase inhibitor-9
Chemical Name: Aurora kinase inhibitor-9
CAS Number: 2419107-09-6
Molecular Formula: C₁₉H₁₇Cl₂N₃O₄S
Molecular Weight: 454.33
Catalog: Signaling Pathways Cell Cycle/DNA Damage Aurora Kinase
Create Date: 2022-09-08 10:45:39
Modify Date: 2024-01-31 13:27:33
Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity[1].

Name	Aurora kinase inhibitor-9

Description	Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Aurora Kinase Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Aurora Kinase
Target	Aurora A:0.093 μM (IC50) Aurora B:0.09 μM (IC50)
References	[1]. Al-Sanea MM, et al. Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights. Bioorg Med Chem. 2020 Jul 1;28(13):115525.

Molecular Formula	C₁₉H₁₇Cl₂N₃O₄S
Molecular Weight	454.33