Aurora inhibitor 1
Modify Date: 2025-08-25 14:33:05
Aurora inhibitor 1 structure
|
Common Name | Aurora inhibitor 1 | ||
|---|---|---|---|---|
| CAS Number | 2227019-45-4 | Molecular Weight | 459.57 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H25N9S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Aurora inhibitor 1Aurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase, respectively[1]. |
| Name | Aurora inhibitor 1 |
|---|
| Description | Aurora inhibitor 1 is a potent Aurora inhibitor with an IC50 of ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
Aurora A:4 nM (IC50) Aurora B:13 nM (IC50) |
| In Vitro | Aurora inhibitor 1 (Compound 16) exhibits Kd values of 0.01 nM for both Aurora A and Aurora B kinase[1]. |
| In Vivo | Aurora inhibitor 1 (Compound 16) exhibits good drug exposure levels across species upon oral dosing, and shows excellent in vivo efficacy in a mouse xenograft tumor model when dosed orally[1]. |
| References |
| Molecular Formula | C23H25N9S |
|---|---|
| Molecular Weight | 459.57 |
| Hazard Codes | Xi |
|---|