Dihydropteroate synthase-IN-1

Modify Date: 2024-01-06 15:51:46

Dihydropteroate synthase-IN-1 structure	Common Name	Dihydropteroate synthase-IN-1
	CAS Number	2418026-70-5	Molecular Weight	449.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₃N₅O₄S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dihydropteroate synthase-IN-1

Dihydropteroate synthase-IN-1 (compound 5g) is a potent dihydropteroate synthase (DHPS) inhibitor. Dihydropteroate synthase-IN-1 shows antimicrobial activities and antifungal activity. Dihydropteroate synthase-IN-1 inhibits cytochromes P450. Dihydropteroate synthase-IN-1 can bu used as diagnostic radio imaging material[1].

Name	Dihydropteroate synthase-IN-1

Description	Dihydropteroate synthase-IN-1 (compound 5g) is a potent dihydropteroate synthase (DHPS) inhibitor. Dihydropteroate synthase-IN-1 shows antimicrobial activities and antifungal activity. Dihydropteroate synthase-IN-1 inhibits cytochromes P450. Dihydropteroate synthase-IN-1 can bu used as diagnostic radio imaging material[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	DHPS[1]
In Vitro	Dihydropteroate synthase-IN-1 (compound 5g) shows antimicrobial activities with MIC of 24.3, 26.3, 22.8, 20.6, 19.6, 23.2 µg/ml for S. pneumoniae, B. Subtilis, S. epidermidis, E. coli, P. vulgaris, K. pneumonia, respectively[1]. Dihydropteroate synthase-IN-1 shows antifungal activity with MIC of 21.6, 20.3, 20.4 µg/ml for A. fumigates, S. racemosum, G. candidum, respectively[1].
References	[1]. Nasr T, et al. New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. Bioorg Med Chem. 2020 May 1;28(9):115444.

Molecular Formula	C₁₉H₂₃N₅O₄S₂
Molecular Weight	449.55

Dihydropteroate synthase-IN-1

Use of Dihydropteroate synthase-IN-1

Names

Dihydropteroate synthase-IN-1 Biological Activity

Chemical & Physical Properties