Name | Dihydropteroate synthase-IN-1 |
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Description | Dihydropteroate synthase-IN-1 (compound 5g) is a potent dihydropteroate synthase (DHPS) inhibitor. Dihydropteroate synthase-IN-1 shows antimicrobial activities and antifungal activity. Dihydropteroate synthase-IN-1 inhibits cytochromes P450. Dihydropteroate synthase-IN-1 can bu used as diagnostic radio imaging material[1]. |
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Related Catalog | |
Target |
DHPS[1] |
In Vitro | Dihydropteroate synthase-IN-1 (compound 5g) shows antimicrobial activities with MIC of 24.3, 26.3, 22.8, 20.6, 19.6, 23.2 µg/ml for S. pneumoniae, B. Subtilis, S. epidermidis, E. coli, P. vulgaris, K. pneumonia, respectively[1]. Dihydropteroate synthase-IN-1 shows antifungal activity with MIC of 21.6, 20.3, 20.4 µg/ml for A. fumigates, S. racemosum, G. candidum, respectively[1]. |
References |
Molecular Formula | C19H23N5O4S2 |
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Molecular Weight | 449.55 |