Thalidomide-amido-PEG2-NH2 hydrochloride
Modify Date: 2025-09-18 13:11:45
Thalidomide-amido-PEG2-NH2 hydrochloride structure
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Common Name | Thalidomide-amido-PEG2-NH2 hydrochloride | ||
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| CAS Number | 2380273-73-2 | Molecular Weight | 454.86 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H23ClN4O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-amido-PEG2-NH2 hydrochlorideThalidomide-amido-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-amido-PEG2-NH2 hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Thalidomide-amido-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C19H23ClN4O7 |
|---|---|
| Molecular Weight | 454.86 |
| InChIKey | RZNSRUSISUGVAE-UHFFFAOYSA-N |
| SMILES | Cl.NCCOCCOCC(=O)Nc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O |
| Hazard Codes | Xi |
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| MFCD32173780 |