Thalidomide-Piperazine-PEG2-NH2 structure
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Common Name | Thalidomide-Piperazine-PEG2-NH2 | ||
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CAS Number | 2357110-14-4 | Molecular Weight | 473.52 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C23H31N5O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Thalidomide-Piperazine-PEG2-NH2Thalidomide-Piperazine-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
Name | Thalidomide-Piperazine-PEG2-NH2 |
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Description | Thalidomide-Piperazine-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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Related Catalog | |
Target |
Cereblon |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
References |
Molecular Formula | C23H31N5O6 |
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Molecular Weight | 473.52 |