CDK7-IN-6

Modify Date: 2024-01-21 23:17:39

CDK7-IN-6 Structure
CDK7-IN-6 structure
Common Name CDK7-IN-6
CAS Number 2378710-04-2 Molecular Weight 524.06
Density N/A Boiling Point N/A
Molecular Formula C26H34ClN9O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK7-IN-6


CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer[1].

 Names

Name CDK7-IN-6

 CDK7-IN-6 Biological Activity

Description CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer[1].
Related Catalog
Target

CDK7:≤100 nM (IC50)

In Vitro CDK7-IN-6 inhibits the viability of HCT116, H460, MV4-11, A2780, and OVCAR cells (IC50≤1 μM)[1].
References

[1]. Kiyean NAM, et al.Preparation of pyrazolotriazine and/or pyrazolopyrimidine derivatives as selective inhibitor of cyclin dependent kinase. WO2019197549 A1.

 Chemical & Physical Properties

Molecular Formula C26H34ClN9O
Molecular Weight 524.06
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: CDK7-IN-6
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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