CDK7-IN-7

Modify Date: 2024-01-02 07:18:17

CDK7-IN-7 Structure
CDK7-IN-7 structure
Common Name CDK7-IN-7
CAS Number 2640208-01-9 Molecular Weight 513.31
Density N/A Boiling Point N/A
Molecular Formula C20H20BrF3N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK7-IN-7


CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nM (Patent CN112661745A, compound T-01)[1].

 Names

Name CDK7-IN-7

 CDK7-IN-7 Biological Activity

Description CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nM (Patent CN112661745A, compound T-01)[1].
Related Catalog
Target

CDK7:<50 nM (IC50)

In Vitro CDK7-IN-7 shows inhibitory against MDA‑MB 231, MDA-MB453, OVCAR3, A2780, HCT-116, WiDr and Calu-6 cells (IC50 ranging from 12.21 to 144.9 nM)[1].
References

[1]. Compounds useful as CDK7 kinase inhibitors and uses thereof. CN112661745A.

 Chemical & Physical Properties

Molecular Formula C20H20BrF3N6O2
Molecular Weight 513.31
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