2640208-01-9
2640208-01-9 structure
- Name: CDK7-IN-7
- Chemical Name: CDK7-IN-7
- CAS Number: 2640208-01-9
- Molecular Formula: C20H20BrF3N6O2
- Molecular Weight: 513.31
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2022-03-05 18:03:07
- Modify Date: 2024-01-02 07:18:17
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CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nM (Patent CN112661745A, compound T-01)[1].
| Name | CDK7-IN-7 |
|---|
| Description | CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nM (Patent CN112661745A, compound T-01)[1]. |
|---|---|
| Related Catalog | |
| Target |
CDK7:<50 nM (IC50) |
| In Vitro | CDK7-IN-7 shows inhibitory against MDA‑MB 231, MDA-MB453, OVCAR3, A2780, HCT-116, WiDr and Calu-6 cells (IC50 ranging from 12.21 to 144.9 nM)[1]. |
| References |
[1]. Compounds useful as CDK7 kinase inhibitors and uses thereof. CN112661745A. |
| Molecular Formula | C20H20BrF3N6O2 |
|---|---|
| Molecular Weight | 513.31 |