K-Ras ligand-Linker Conjugate 3
Modify Date: 2025-08-27 20:09:38
K-Ras ligand-Linker Conjugate 3 structure
|
Common Name | K-Ras ligand-Linker Conjugate 3 | ||
|---|---|---|---|---|
| CAS Number | 2378261-87-9 | Molecular Weight | 944.15 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C49H65N7O10S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of K-Ras ligand-Linker Conjugate 3K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1]. |
| Name | K-Ras ligand-Linker Conjugate 3 |
|---|
| Description | K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Andrew P. Crew, et al. Modulators of proteolysis and associated methods of use. WO2019195609A2. |
| Molecular Formula | C49H65N7O10S |
|---|---|
| Molecular Weight | 944.15 |
| Hazard Codes | Xi |
|---|