K-Ras ligand-Linker Conjugate 3

Names

[ Name ]:
K-Ras ligand-Linker Conjugate 3

Biological Activity

[Description]:

K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Andrew P. Crew, et al. Modulators of proteolysis and associated methods of use. WO2019195609A2.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₉H₆₅N₇O₁₀S

[ Molecular Weight ]:
944.15

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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