(S,R,S)-AHPC-C4-NH2 dihydrochloride

Modify Date: 2025-08-27 11:42:03

(S,R,S)-AHPC-C4-NH2 dihydrochloride structure	Common Name	(S,R,S)-AHPC-C4-NH2 dihydrochloride
	CAS Number	2341796-78-7	Molecular Weight	602.62
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₄₁Cl₂N₅O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (S,R,S)-AHPC-C4-NH2 dihydrochloride

(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

Name	(S,R,S)-AHPC-C4-NH2 dihydrochloride

Description	(S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.

Molecular Formula	C₂₇H₄₁Cl₂N₅O₄S
Molecular Weight	602.62
InChIKey	QBJGQVIKGJREIR-UHFFFAOYSA-N
SMILES	Cc1ncsc1-c1ccc(CNC(=O)C2CC(O)CN2C(=O)C(NC(=O)CCCCN)C(C)(C)C)cc1.Cl.Cl

Hazard Codes	Xi

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