(S,R,S)-AHPC-C2-NH2 dihydrochloride

Modify Date: 2024-04-02 19:59:08

(S,R,S)-AHPC-C2-NH2 dihydrochloride structure	Common Name	(S,R,S)-AHPC-C2-NH2 dihydrochloride
	CAS Number	2341796-73-2	Molecular Weight	574.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₇Cl₂N₅O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (S,R,S)-AHPC-C2-NH2 dihydrochloride

(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1].

Name	(S,R,S)-AHPC-C2-NH2 dihydrochloride

Description	(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1.

Molecular Formula	C₂₅H₃₇Cl₂N₅O₄S
Molecular Weight	574.56

Hazard Codes	Xi

DC Chemicals Limited
China
Product Name: (S,R,S)-AHPC-C2-NH2 dihydrochloride
Price: $650.0/100mg $1100.0/250mg $2000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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