2341796-73-2

2341796-73-2 structure

Name: (S,R,S)-AHPC-C2-NH2 dihydrochloride
Chemical Name: (S,R,S)-AHPC-C2-NH2 dihydrochloride
CAS Number: 2341796-73-2
Molecular Formula: C₂₅H₃₇Cl₂N₅O₄S
Molecular Weight: 574.56
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-08-08 08:32:13
Modify Date: 2024-04-02 19:59:08
(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1].

Name	(S,R,S)-AHPC-C2-NH2 dihydrochloride

Description	(S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1.

Molecular Formula	C₂₅H₃₇Cl₂N₅O₄S
Molecular Weight	574.56

Hazard Codes	Xi