BMS-905
Modify Date: 2025-08-25 21:23:53
BMS-905 structure
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Common Name | BMS-905 | ||
|---|---|---|---|---|
| CAS Number | 2205846-49-5 | Molecular Weight | 347.506 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H29N3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BMS-905BMS-905 is a potent dual inhibitor of TLR7 and TLR8 with IC50 of 0.3 nM (TLR7, IL-6 inhibition in mouse blood), shows good selectivity against TLR9 and other TLR family members. |
| Name | BMS-905 |
|---|
| Description | BMS-905 is a potent dual inhibitor of TLR7 and TLR8 with IC50 of 0.3 nM (TLR7, IL-6 inhibition in mouse blood), shows good selectivity against TLR9 and other TLR family members. |
|---|---|
| References | 1. Ratna Kumar Sreekantha, et al. ACS Medicinal Chemistry Letters. DOI: 10.1021/acsmedchemlett.2c00049 |
| Molecular Formula | C23H29N3 |
|---|---|
| Molecular Weight | 347.506 |
| InChIKey | XSXCQWXAFRASGU-UHFFFAOYSA-N |
| SMILES | Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C)n1 |