2205846-49-5
2205846-49-5 structure
- Name: BMS-905
- Chemical Name: BMS-905
- CAS Number: 2205846-49-5
- Molecular Formula: C23H29N3
- Molecular Weight: 347.506
- Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
- Create Date: 2022-07-01 19:33:47
- Modify Date: 2025-08-25 21:23:53
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BMS-905 is a potent dual inhibitor of TLR7 and TLR8 with IC50 of 0.3 nM (TLR7, IL-6 inhibition in mouse blood), shows good selectivity against TLR9 and other TLR family members.
| Name | BMS-905 |
|---|
| Description | BMS-905 is a potent dual inhibitor of TLR7 and TLR8 with IC50 of 0.3 nM (TLR7, IL-6 inhibition in mouse blood), shows good selectivity against TLR9 and other TLR family members. |
|---|---|
| References | 1. Ratna Kumar Sreekantha, et al. ACS Medicinal Chemistry Letters. DOI: 10.1021/acsmedchemlett.2c00049 |
| Molecular Formula | C23H29N3 |
|---|---|
| Molecular Weight | 347.506 |