BMS-905

Names

[ CAS No. ]:
2205846-49-5

[ Name ]:
BMS-905

Biological Activity

[Description]:

BMS-905 is a potent dual inhibitor of TLR7 and TLR8 with IC50 of 0.3 nM (TLR7, IL-6 inhibition in mouse blood), shows good selectivity against TLR9 and other TLR family members.

[References]

1. Ratna Kumar Sreekantha, et al. ACS Medicinal Chemistry Letters. DOI: 10.1021/acsmedchemlett.2c00049

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₉N₃

[ Molecular Weight ]:
347.506

Related Compounds

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