Ac-YVAD-AFC

Modify Date: 2025-08-23 10:51:04

Ac-YVAD-AFC Structure
Ac-YVAD-AFC structure
Common Name Ac-YVAD-AFC
CAS Number 219137-85-6 Molecular Weight 719.662
Density 1.4±0.1 g/cm3 Boiling Point 1084.6±65.0 °C at 760 mmHg
Molecular Formula C33H36F3N5O10 Melting Point N/A
MSDS N/A Flash Point 609.8±34.3 °C

 Use of Ac-YVAD-AFC


Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1and caspase-4, with λ excitation of 400 nm and λ emission of 505 nm[1][2].

 Names

Name 4-[[4-(difluoromethyl)-2-oxochromen-7-yl]amino]-3-[2-(3-methylbutanoylamino)propanoylamino]-4-oxobutanoic acid
Synonym More Synonyms

 Ac-YVAD-AFC Biological Activity

Description Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1and caspase-4, with λ excitation of 400 nm and λ emission of 505 nm[1][2].
Related Catalog

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1084.6±65.0 °C at 760 mmHg
Molecular Formula C33H36F3N5O10
Molecular Weight 719.662
Flash Point 609.8±34.3 °C
Exact Mass 719.241455
PSA 233.24000
LogP 3.10
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.586
InChIKey GWKJISJKNKIJNP-DEQDFGQZSA-N
SMILES CC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)Nc1ccc2c(C(F)(F)F)cc(=O)oc2c1)C(C)C

 Synonyms

N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-α-asparagine
L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-
Ac-Tyr-Val-Ala-Asp-AFC
Ac-YVAD-AFC
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