Ac-YVAD-pNA

Modify Date: 2025-08-22 20:35:25

Ac-YVAD-pNA structure	Common Name	Ac-YVAD-pNA
	CAS Number	149231-66-3	Molecular Weight	628.63
	Density	1.4±0.1 g/cm3	Boiling Point	1108.9±65.0 °C at 760 mmHg
	Molecular Formula	C₂₉H₃₆N₆O₁₀	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	624.5±34.3 °C

Use of Ac-YVAD-pNA

Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes[1][2].

Name	(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-(4-nitroanilino)-4-oxobutanoic acid
Synonym	More Synonyms

Description	Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Inflammation/Immunology
Target	Caspase-1
References	[1]. Pereira NA, et al. Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity. Biochem Biophys Res Commun. 2008 Dec 19;377(3):873-7. [2]. Xin W, Wang Q, et al. A new mechanism of inhibition of IL-1β secretion by celastrol through the NLRP3 inflammasome pathway. Eur J Pharmacol. 2017 Nov 5;814:240-247.

Density	1.4±0.1 g/cm3
Boiling Point	1108.9±65.0 °C at 760 mmHg
Molecular Formula	C₂₉H₃₆N₆O₁₀
Molecular Weight	628.63
Flash Point	624.5±34.3 °C
Exact Mass	628.249268
PSA	248.85000
LogP	2.61
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.605

RIDADR	NONH for all modes of transport

Ac-Tyr-Val-Ala-Asp-PNA

IL-1beta Converting Enzyme (ICE) Colorimetric Substrate

Ac-Tyr-Val-Ala-Asp-paranitroanilide

L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-

N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine

Caspase-1 Substrate IV,Colorimetric

Ac-YVAD-pNA

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ac-YVAD-pNA
Price: Check
Purity: 97.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Nanjing Peptide Biotech Ltd
China
Product Name: Ac-Tyr-Val-Ala-Asp-pNA
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Delivery: 7 Day
Contact: jom
Email: chenglong.fan@njpeptide.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: AC-YVAD-PNA
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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