Biotin-PEG8-alcohol

Modify Date: 2024-01-10 12:28:54

Biotin-PEG8-alcohol Structure
Biotin-PEG8-alcohol structure
Common Name Biotin-PEG8-alcohol
CAS Number 2182601-20-1 Molecular Weight 595.75
Density N/A Boiling Point N/A
Molecular Formula C26H49N3O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG8-alcohol


Biotin-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG8-alcohol

 Biotin-PEG8-alcohol Biological Activity

Description Biotin-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C26H49N3O10S
Molecular Weight 595.75