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1345337-22-5

1345337-22-5 structure
1345337-22-5 structure
  • Name: N-Boc-PEG8-alcohol
  • Chemical Name: Z-8-aMino-3,6-dioxaoctanoic acid
  • CAS Number: 1345337-22-5
  • Molecular Formula: C21H43NO10
  • Molecular Weight: 297.30376
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-14 04:41:38
  • Modify Date: 2024-01-09 18:50:26
  • N-Boc-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Z-8-aMino-3,6-dioxaoctanoic acid
Synonyms CBZ-8-AMINO-3,6-DIOXAOCTANOIC ACID
Description N-Boc-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C21H43NO10
Molecular Weight 297.30376