SN38-COOH

Modify Date: 2024-04-06 16:46:00

SN38-COOH structure	Common Name	SN38-COOH
	CAS Number	2170118-23-5	Molecular Weight	492.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₄N₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SN38-COOH

SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2].

Name	SN38-COOH

Description	SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2].
Related Catalog	Research Areas >> Cancer
References	[1]. Wilson Lim, et al. Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. PLoS Negl Trop Dis. 2018 Apr 26;12(4):e0006437. [2]. Wallin A, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8.

Description

SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2].

Related Catalog

Research Areas >> Cancer

References

[1]. Wilson Lim, et al. Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. PLoS Negl Trop Dis. 2018 Apr 26;12(4):e0006437.

[2]. Wallin A, et al. Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep. 2008 Jun;19(6):1493-8.

Molecular Formula	C₂₆H₂₄N₂O₈
Molecular Weight	492.48

SN38-COOH

Use of SN38-COOH

Names

SN38-COOH Biological Activity

Chemical & Physical Properties