Apalutamide-COOH

Modify Date: 2025-08-27 10:57:42

Apalutamide-COOH Structure
Apalutamide-COOH structure
Common Name Apalutamide-COOH
CAS Number 1332391-04-4 Molecular Weight 464.39
Density N/A Boiling Point N/A
Molecular Formula C20H12F4N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Apalutamide-COOH


Apalutamide-COOH can be used to synthesis Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].

 Names

Name Apalutamide-COOH

 Apalutamide-COOH Biological Activity

Description Apalutamide-COOH can be used to synthesis Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].
Related Catalog
References

[1]. Nicholas D. Smith, et al. Androgen receptor modulators and uses thereof. WO2011103202A2.

 Chemical & Physical Properties

Molecular Formula C20H12F4N4O3S
Molecular Weight 464.39
InChIKey ICXCBGDFYFFSGX-UHFFFAOYSA-N
SMILES N#Cc1ncc(N2C(=O)C3(CCC3)N(c3ccc(C(=O)O)c(F)c3)C2=S)cc1C(F)(F)F
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