CL2E-SN38
Modify Date: 2025-08-26 19:26:36
CL2E-SN38 structure
|
Common Name | CL2E-SN38 | ||
|---|---|---|---|---|
| CAS Number | 1639139-65-3 | Molecular Weight | 1731.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C86H118N14O24 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CL2E-SN38CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1]. |
| Name | CL2E-SN38 |
|---|
| Description | CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C86H118N14O24 |
|---|---|
| Molecular Weight | 1731.94 |
| InChIKey | DBJJGJOYBNMURS-GCALBSARSA-N |
| SMILES | CCc1c2c(nc3ccc(OC(=O)N(C)CCN(C)C(=O)OCc4ccc(NC(=O)C(CCCCN)NC(=O)C(Cc5ccccc5)NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCn5cc(CNC(=O)C6CCC(CN7C(=O)C=CC7=O)CC6)nn5)cc4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC |