CL2-MMT-SN38

Modify Date: 2025-08-26 18:32:35

CL2-MMT-SN38 Structure
CL2-MMT-SN38 structure
Common Name CL2-MMT-SN38
CAS Number 1084888-82-3 Molecular Weight 1900.13
Density N/A Boiling Point N/A
Molecular Formula C102H122N12O24 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CL2-MMT-SN38


CL2-MMT-SN38 is a SN-38 derivative. SN-38, an anticancer agent, is an active metabolite of the Topoisomerase I inhibitor Irinotecan (CPT-11)[1].

 Names

Name CL2-MMT-SN38

 CL2-MMT-SN38 Biological Activity

Description CL2-MMT-SN38 is a SN-38 derivative. SN-38, an anticancer agent, is an active metabolite of the Topoisomerase I inhibitor Irinotecan (CPT-11)[1].
Related Catalog
References

[1]. Moon SJ, et al. Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy. J Med Chem. 2008;51(21):6916-6926.

 Chemical & Physical Properties

Molecular Formula C102H122N12O24
Molecular Weight 1900.13
InChIKey VBYLWGSFLJAJSE-WSVVYDBCSA-N
SMILES CCc1c2c(nc3ccc(O)cc13)-c1cc3c(c(=O)n1C2)COC(=O)C3(CC)OC(=O)OCc1ccc(NC(=O)C(CCCCNC(c2ccccc2)(c2ccccc2)c2ccc(OC)cc2)NC(=O)C(Cc2ccccc2)NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCn2cc(CNC(=O)C3CCC(CN4C(=O)C=CC4=O)CC3)nn2)cc1
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