CL2 Linker structure
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Common Name | CL2 Linker | ||
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CAS Number | 2270986-66-6 | Molecular Weight | 1426.61 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C68H103N11O22 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of CL2 LinkerCL2 Linker is an ADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2]. |
Name | CL2 Linker |
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Description | CL2 Linker is an ADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2]. |
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Related Catalog | |
Target |
Alkyl/ether |
References |
Molecular Formula | C68H103N11O22 |
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Molecular Weight | 1426.61 |