Dox-Ph-PEG1-Cl

Modify Date: 2024-01-31 03:33:26

Dox-Ph-PEG1-Cl Structure
Dox-Ph-PEG1-Cl structure
Common Name Dox-Ph-PEG1-Cl
CAS Number 773095-86-6 Molecular Weight 228.67
Density N/A Boiling Point N/A
Molecular Formula C11H13ClO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dox-Ph-PEG1-Cl


PROTAC Linker 34 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 34 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name PROTAC Linker 34

 Dox-Ph-PEG1-Cl Biological Activity

Description PROTAC Linker 34 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 34 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.

 Chemical & Physical Properties

Molecular Formula C11H13ClO3
Molecular Weight 228.67
Storage condition 2-8°C
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